diff --git a/source/blender/editors/interface/interface_handlers.cc b/source/blender/editors/interface/interface_handlers.cc
index 9a9c0d84160..0b8f1eff190 100644
--- a/source/blender/editors/interface/interface_handlers.cc
+++ b/source/blender/editors/interface/interface_handlers.cc
@@ -11692,6 +11692,9 @@ void UI_screen_free_active_but_highlight(const bContext *C, bScreen *screen)
 uiBut *UI_but_active_drop_name_button(const bContext *C)
 {
   ARegion *region = CTX_wm_region(C);
+  if (region == nullptr) {
+    return nullptr;
+  }
   uiBut *but = ui_region_find_active_but(region);
 
   if (but) {
diff --git a/source/blender/editors/space_node/node_add.cc b/source/blender/editors/space_node/node_add.cc
index 0e3e6f0ece9..c732edb424c 100644
--- a/source/blender/editors/space_node/node_add.cc
+++ b/source/blender/editors/space_node/node_add.cc
@@ -136,6 +136,12 @@ struct RerouteCutsForSocket {
 static int add_reroute_exec(bContext *C, wmOperator *op)
 {
   const ARegion &region = *CTX_wm_region(C);
+
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   SpaceNode &snode = *CTX_wm_space_node(C);
   bNodeTree &ntree = *snode.edittree;
   const Span<float2> socket_locations = snode.runtime->all_socket_locations;
@@ -341,6 +347,11 @@ static int node_add_group_invoke(bContext *C, wmOperator *op, const wmEvent *eve
   ARegion *region = CTX_wm_region(C);
   SpaceNode *snode = CTX_wm_space_node(C);
 
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   /* Convert mouse coordinates to v2d space. */
   UI_view2d_region_to_view(&region->v2d,
                            event->mval[0],
@@ -423,6 +434,11 @@ static int node_add_group_asset_invoke(bContext *C, wmOperator *op, const wmEven
   ARegion &region = *CTX_wm_region(C);
   SpaceNode &snode = *CTX_wm_space_node(C);
 
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   const AssetLibraryReference *library_ref = CTX_wm_asset_library_ref(C);
   if (!library_ref) {
     return OPERATOR_CANCELLED;
@@ -517,6 +533,11 @@ static int node_add_object_invoke(bContext *C, wmOperator *op, const wmEvent *ev
   ARegion *region = CTX_wm_region(C);
   SpaceNode *snode = CTX_wm_space_node(C);
 
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   /* Convert mouse coordinates to v2d space. */
   UI_view2d_region_to_view(&region->v2d,
                            event->mval[0],
@@ -719,6 +740,11 @@ static int node_add_file_invoke(bContext *C, wmOperator *op, const wmEvent *even
   ARegion *region = CTX_wm_region(C);
   SpaceNode *snode = CTX_wm_space_node(C);
 
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   /* Convert mouse coordinates to `v2d` space. */
   UI_view2d_region_to_view(&region->v2d,
                            event->mval[0],
@@ -924,6 +950,11 @@ static int node_add_search_invoke(bContext *C, wmOperator *op, const wmEvent *ev
 {
   const ARegion &region = *CTX_wm_region(C);
 
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   float2 cursor;
   UI_view2d_region_to_view(&region.v2d, event->mval[0], event->mval[1], &cursor.x, &cursor.y);
 
diff --git a/source/blender/editors/space_node/node_edit.cc b/source/blender/editors/space_node/node_edit.cc
index 54dc0772c96..e9cdbb4f4c0 100644
--- a/source/blender/editors/space_node/node_edit.cc
+++ b/source/blender/editors/space_node/node_edit.cc
@@ -907,6 +907,12 @@ static int node_resize_modal(bContext *C, wmOperator *op, const wmEvent *event)
 {
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   bNode *node = nodeGetActive(snode->edittree);
   NodeSizeWidget *nsw = (NodeSizeWidget *)op->customdata;
 
@@ -1011,6 +1017,12 @@ static int node_resize_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   const bNode *node = nodeGetActive(snode->edittree);
 
   if (node == nullptr) {
diff --git a/source/blender/editors/space_node/node_relationships.cc b/source/blender/editors/space_node/node_relationships.cc
index 73cc64bbf61..ab5d4cc66c1 100644
--- a/source/blender/editors/space_node/node_relationships.cc
+++ b/source/blender/editors/space_node/node_relationships.cc
@@ -21,6 +21,7 @@
 #include "BKE_node.h"
 #include "BKE_node_runtime.hh"
 #include "BKE_node_tree_update.h"
+#include "BKE_report.h"
 #include "BKE_screen.h"
 
 #include "ED_node.hh" /* own include */
@@ -1329,6 +1330,11 @@ static int node_link_invoke(bContext *C, wmOperator *op, const wmEvent *event)
   SpaceNode &snode = *CTX_wm_space_node(C);
   ARegion &region = *CTX_wm_region(C);
 
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   bool detach = RNA_boolean_get(op->ptr, "detach");
 
   int2 mval;
@@ -1454,6 +1460,11 @@ static int cut_links_exec(bContext *C, wmOperator *op)
   SpaceNode &snode = *CTX_wm_space_node(C);
   const ARegion &region = *CTX_wm_region(C);
 
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   Vector<float2> path;
   RNA_BEGIN (op->ptr, itemptr, "path") {
     float2 loc_region;
@@ -1562,6 +1573,12 @@ static int mute_links_exec(bContext *C, wmOperator *op)
   Main &bmain = *CTX_data_main(C);
   SpaceNode &snode = *CTX_wm_space_node(C);
   const ARegion &region = *CTX_wm_region(C);
+
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   bNodeTree &ntree = *snode.edittree;
   const Span<float2> socket_locations = snode.runtime->all_socket_locations;
 
@@ -1866,9 +1883,15 @@ static bNode *node_find_frame_to_attach(ARegion &region,
   return nullptr;
 }
 
-static int node_attach_invoke(bContext *C, wmOperator * /*op*/, const wmEvent *event)
+static int node_attach_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   ARegion &region = *CTX_wm_region(C);
+
+  if (&region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   SpaceNode &snode = *CTX_wm_space_node(C);
   bNodeTree &ntree = *snode.edittree;
   bNode *frame = node_find_frame_to_attach(region, ntree, event->mval);
@@ -2562,13 +2585,20 @@ static int node_insert_offset_invoke(bContext *C, wmOperator *op, const wmEvent
     return OPERATOR_CANCELLED;
   }
 
+  ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   BLI_assert((snode->flag & SNODE_SKIP_INSOFFSET) == 0);
 
   iofsd->ntree = snode->edittree;
   iofsd->anim_timer = WM_event_add_timer(CTX_wm_manager(C), CTX_wm_window(C), TIMER, 0.02);
 
   node_link_insert_offset_ntree(
-      iofsd, CTX_wm_region(C), event->mval, (snode->insert_ofs_dir == SNODE_INSERTOFS_DIR_RIGHT));
+      iofsd, region, event->mval, (snode->insert_ofs_dir == SNODE_INSERTOFS_DIR_RIGHT));
 
   /* add temp handler */
   WM_event_add_modal_handler(C, op);
diff --git a/source/blender/editors/space_node/node_select.cc b/source/blender/editors/space_node/node_select.cc
index 663a235b834..9edc8c6a1d3 100644
--- a/source/blender/editors/space_node/node_select.cc
+++ b/source/blender/editors/space_node/node_select.cc
@@ -24,6 +24,7 @@
 #include "BKE_node.h"
 #include "BKE_node_runtime.hh"
 #include "BKE_node_tree_update.h"
+#include "BKE_report.h"
 #include "BKE_workspace.h"
 
 #include "ED_node.h"  /* own include */
@@ -1239,6 +1240,12 @@ static int node_select_same_type_step_exec(bContext *C, wmOperator *op)
 {
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   const bool prev = RNA_boolean_get(op->ptr, "prev");
   bNode &active_node = *nodeGetActive(snode->edittree);
 
diff --git a/source/blender/editors/space_node/node_view.cc b/source/blender/editors/space_node/node_view.cc
index b11997ba1b6..abefa48f69c 100644
--- a/source/blender/editors/space_node/node_view.cc
+++ b/source/blender/editors/space_node/node_view.cc
@@ -17,6 +17,7 @@
 #include "BKE_main.h"
 #include "BKE_node.h"
 #include "BKE_node_runtime.hh"
+#include "BKE_report.h"
 #include "BKE_screen.h"
 
 #include "ED_image.h"
@@ -110,6 +111,12 @@ bool space_node_view_flag(
 static int node_view_all_exec(bContext *C, wmOperator *op)
 {
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   SpaceNode *snode = CTX_wm_space_node(C);
   const int smooth_viewtx = WM_operator_smooth_viewtx_get(op);
 
@@ -147,6 +154,12 @@ void NODE_OT_view_all(wmOperatorType *ot)
 static int node_view_selected_exec(bContext *C, wmOperator *op)
 {
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   SpaceNode *snode = CTX_wm_space_node(C);
   const int smooth_viewtx = WM_operator_smooth_viewtx_get(op);
 
@@ -238,6 +251,12 @@ static int snode_bg_viewmove_invoke(bContext *C, wmOperator *op, const wmEvent *
   Main *bmain = CTX_data_main(C);
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   NodeViewMove *nvm;
   Image *ima;
   ImBuf *ibuf;
@@ -307,6 +326,12 @@ static int backimage_zoom_exec(bContext *C, wmOperator *op)
 {
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
+
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   float fac = RNA_float_get(op->ptr, "factor");
 
   snode->zoom *= fac;
@@ -342,12 +367,17 @@ void NODE_OT_backimage_zoom(wmOperatorType *ot)
 /** \name Background Image Fit
  * \{ */
 
-static int backimage_fit_exec(bContext *C, wmOperator * /*op*/)
+static int backimage_fit_exec(bContext *C, wmOperator *op)
 {
   Main *bmain = CTX_data_main(C);
   SpaceNode *snode = CTX_wm_space_node(C);
   ARegion *region = CTX_wm_region(C);
 
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   Image *ima;
   ImBuf *ibuf;
 
@@ -644,6 +674,11 @@ static int sample_invoke(bContext *C, wmOperator *op, const wmEvent *event)
   ARegion *region = CTX_wm_region(C);
   ImageSampleInfo *info;
 
+  if (region == nullptr) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   /* Don't handle events intended for nodes (which rely on click/drag distinction).
    * which this operator would use since sampling is normally activated on press, see: #98191. */
   if (node_or_socket_isect_event(*C, *event)) {
diff --git a/source/blender/windowmanager/intern/wm_gesture_ops.c b/source/blender/windowmanager/intern/wm_gesture_ops.c
index ae8c446bd87..5cf23172b9f 100644
--- a/source/blender/windowmanager/intern/wm_gesture_ops.c
+++ b/source/blender/windowmanager/intern/wm_gesture_ops.c
@@ -19,6 +19,7 @@
 #include "BLI_rect.h"
 
 #include "BKE_context.h"
+#include "BKE_report.h"
 
 #include "WM_api.h"
 #include "WM_types.h"
@@ -164,6 +165,12 @@ int WM_gesture_box_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   wmWindow *win = CTX_wm_window(C);
   const ARegion *region = CTX_wm_region(C);
+
+  if (region == NULL) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   const bool wait_for_input = !WM_event_is_mouse_drag_or_press(event) &&
                               RNA_boolean_get(op->ptr, "wait_for_input");
 
@@ -286,10 +293,17 @@ static void gesture_circle_apply(bContext *C, wmOperator *op);
 int WM_gesture_circle_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   wmWindow *win = CTX_wm_window(C);
+  const ARegion *region = CTX_wm_region(C);
+
+  if (region == NULL) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
   const bool wait_for_input = !WM_event_is_mouse_drag_or_press(event) &&
                               RNA_boolean_get(op->ptr, "wait_for_input");
 
-  op->customdata = WM_gesture_new(win, CTX_wm_region(C), event, WM_GESTURE_CIRCLE);
+  op->customdata = WM_gesture_new(win, region, event, WM_GESTURE_CIRCLE);
   wmGesture *gesture = op->customdata;
   rcti *rect = gesture->customdata;
 
@@ -477,9 +491,15 @@ void WM_OT_circle_gesture(wmOperatorType *ot)
 int WM_gesture_lasso_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   wmWindow *win = CTX_wm_window(C);
+  ARegion *region = CTX_wm_region(C);
   PropertyRNA *prop;
 
-  op->customdata = WM_gesture_new(win, CTX_wm_region(C), event, WM_GESTURE_LASSO);
+  if (region == NULL) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
+  op->customdata = WM_gesture_new(win, region, event, WM_GESTURE_LASSO);
 
   /* add modal handler */
   WM_event_add_modal_handler(C, op);
@@ -496,9 +516,15 @@ int WM_gesture_lasso_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 int WM_gesture_lines_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   wmWindow *win = CTX_wm_window(C);
+  ARegion *region = CTX_wm_region(C);
   PropertyRNA *prop;
 
-  op->customdata = WM_gesture_new(win, CTX_wm_region(C), event, WM_GESTURE_LINES);
+  if (region == NULL) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
+  op->customdata = WM_gesture_new(win, region, event, WM_GESTURE_LINES);
 
   /* add modal handler */
   WM_event_add_modal_handler(C, op);
@@ -736,9 +762,15 @@ static bool gesture_straightline_apply(bContext *C, wmOperator *op)
 int WM_gesture_straightline_invoke(bContext *C, wmOperator *op, const wmEvent *event)
 {
   wmWindow *win = CTX_wm_window(C);
+  ARegion *region = CTX_wm_region(C);
   PropertyRNA *prop;
 
-  op->customdata = WM_gesture_new(win, CTX_wm_region(C), event, WM_GESTURE_STRAIGHTLINE);
+  if (region == NULL) {
+    BKE_report(op->reports, RPT_ERROR_INVALID_CONTEXT, "Missing 'region' in context");
+    return OPERATOR_CANCELLED;
+  }
+
+  op->customdata = WM_gesture_new(win, region, event, WM_GESTURE_STRAIGHTLINE);
 
   if (WM_event_is_mouse_drag_or_press(event)) {
     wmGesture *gesture = op->customdata;